City Inn has partnered with Diamond Advertising to overhaul the brand. A campaign to support the rebrand is currently under discussion.
City Inn said it did not feel the company's name reflected the 'stylish, modern and upmarket' experience that customers associate with the hotels.
The rebrand comes as the company expands internationally, opening a 553-room hotel in Amsterdam. It is also opening new premises near the Tower of London.
David Orr, chief executive and co-founder of the company, said: "Mint Hotel gives us an instantly memorable identity to embrace the quality and modernity of what we do and reflects the brand's sector-leading qualities paving the way for the growth of our business.
"We believe it will resonate well with our current guests, reflecting our true position as a class leading, innovative and stylish city centre hotel brand."
The City Inn hotel chain was co-founded by the Orr family and the Bank of Scotland in 1995. It has eight hotels in Bristol, Birmingham, Manchester, Glasgow, Leeds, and London.