The initiative is a manifestation of P&G chief Chris de Lapuente's strategy to take marketing spend below the line to create more meaningful communication with consumers.
The CD magazine will feature seven five-minute radio-style programmes on women's health, fitness and stress management.
The content will not promote P&G products, but the CD will be bundled with a book of coupons worth between £3 and £6 off products including Ariel and Bold, Always feminine hygiene, Fairy dishwashing tablets and Olay moisturising cream.
According to Take Five brand manager Simon Brady, the idea behind the initiative is to establish an emotional bond with P&G's core consumer by encouraging her to take a break.
A freephone number will allow recipients to enter competitions, leave comments and questions and submit recipe ideas.
Four CD magazines will be mailed out in a year, at two-month intervals starting later this month. The magazine and direct mail campaign has been created by Saatchi & Saatchi.
The first issue features tracks on yoga, colour therapy for the home and wardrobe, women's health, a recipe for fruit smoothies presented by TV chef Lesley Walters and a feature on the best books to take on holiday, produced in conjunction with Penguin.
The CD is introduced by P&G employee Vicky Nicholson, the 37-year-old mother of three who came up with the Take Five concept.
P&G will make a donation to women's and children's charity WellBeing for each coupon redeemed.
The FMCG giant boasted the UK's second biggest adspend last year - £114.2m, of which £28.6m went to DM.