The launch is part of the company's strategy to double the size of its energy drink portfolio in 2006.
In 2000 Coca-Cola introduced Burn, a niche energy drink that was sold primarily in bars and was viewed as a direct challenge to Red Bull. It recently launched an energy version of Sprite called 3G.
Advance by Powerade combines the key ingredients of sports drinks and energy drinks. It will appear in the US in January, and is expected to debut in the UK a few months later.
A spokeswoman for Coca-Cola said: 'We will continue to evaluate opportunities to extend and build on Powerade's success in the UK.'