The actor is following in the footsteps of fellow A-listers Eva Mendes and Eva Longoria by appearing in ads for the Unilever-owned premium Magnum brand.
The TV spots will break in the UK next month as part of a £3m investment in the launch of the Gold variant.
Magnum Gold is being promoted by Unilever as an "indulgent" mix of smooth Madagascan vanilla ice cream and caramel in "crackling golden dipped milk chocolate". The product will be individually priced £1.50; a pack of three will cost £2.49.
Puerto Rico-born del Toro shot to international fame in films including 'Licence to Kill', 'The Usual Suspects', 'Fear and Loathing in Las Vegas' and 'Snatch'.